Cyclobenzaprine Flexeril Side Effects, Interactions, Uses, Dosage, Warnings
If they’re more severe or don’t go away, talk with your doctor or pharmacist. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist.
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Older adults may be more sensitive to the side effects of this drug, especially drowsiness, confusion, constipation, or trouble urinating. Drowsiness and confusion can increase the risk of falling. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Flexeril usually takes between 45 minutes to an hour to work after being ingested to show relaxation activity. It peaks at around 3 to 4 hours, and then the effects begin to wear off.
If any of these effects last or get worse, tell your doctor or pharmacist promptly. Flexeril is a muscle relaxant and works by blocking the pathways of the neurotransmitters that signal pain. It is not an anti-inflammatory drug and does not reduce any inflammation to provide muscle relief. Both of them are used for pain relief but have different mechanisms. In most cases, it is advised not to take an anti-inflammatory drug and a muscle relaxant simultaneously, as they might be contra-indicated. It is not controlled under the Controlled Substances Act (CSA), either.
What Are Side Effects Associated with Using Cyclobenzaprine?
Cyclobenzaprine is structurally and pharmacologically related to tricyclic antidepressants. Among the most dreaded toxicities linked with cyclical antidepressants, overdoses affect fast-acting sodium channels in the cardiac conduction system. Cyclical antidepressants block the cardiac sodium channel and cause prolongation of cardiac depolarization, which manifests as QRS widening on electrocardiograms. There is also evidence that cyclical antidepressants may decrease the seizure threshold by interfering with chloride conductance on the GABA receptor.
The generic form was first approved in 1977 and is sold in both immediate and extended release versions. Call your doctor or local poison control center if you think you’ve taken too much of this drug. Call 911 or go to the nearest emergency room immediately if your symptoms are severe. Taking this drug with an MAOI or within 14 days of stopping an MAOI could increase your risk of serious side effects. If these effects are mild, they may go away within a few days or a couple of weeks.
Depending on the type of muscle relaxer, there are different forms in which you can take them, such as tablets, capsules, solutions or injections. Baclofen is considered the first-line treatment for spasticity, especially for adults who have spinal cord injuries. Cyclobenzaprine is not a narcotic or an opioid, and is not scheduled by the DEA. That being said, dependency can develop if directions and dosage aren’t followed, so be careful to use this drug only as directed by your doctor. Cyclobenzaprine – including Flexeril and Amrixz – is not a narcotic drug or scheduled by the Drug Enforcement Agency.
- You should not need a new prescription for this medication to be refilled.
- Along with its needed effects, a medicine may cause some unwanted effects.
- Check with your physician for additional information about side effects.
- In such patients FLEXERIL should be initiated with a 5 mg dose and titrated slowly upward.
- Providers mainly prescribe antispasmodic skeletal muscle relaxants for musculoskeletal and myofascial pain, especially lower back pain, and muscle spasms.
A post-marketing surveillance program was carried out in 7607 patients with acute musculoskeletal disorders, and included 297 patients treated with FLEXERIL 10 mg for 30 days or longer. The overall effectiveness of FLEXERIL was similar to that observed in the double-blind controlled studies; the overall incidence of adverse effects was less (see ADVERSE REACTIONS). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products.
Highlights for Cyclobenzaprine
As with all medications, the costs of cyclobenzaprine can vary. Cyclobenzaprine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
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Cyclobenzaprine HCl relieves skeletal muscle spasm of local origin without interfering with muscle function. It is ineffective in muscle spasm due to central nervous system how long does a flexeril last disease. At oral doses of up to 10 times the human dose, cyclobenzaprine did not adversely affect the reproductive performance or fertility of male or female rats.
Flexeril is typically used in conjunction with physical therapy or exercise and other forms of treatment for applicable conditions. The extended-release formulation should be administered at the same time each day. The capsule may be swallowed whole, but its contents also may be sprinkled onto a tablespoon of applesauce for immediate consumption without chewing the granules. The patient should rinse their mouth to ensure that they have swallowed all the contents. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use.